The science behind Zooki
Zooki is clinically proven to perform 4x better than conventional supplements - all thanks to our unique, patented nutrient delivery systems. Our nutrient delivery systems harness the power of liposomes to enhance the absorption and bioavailability of nutrients throughout the body. We've compiled this summary to talk you through exactly how it all works.
Liposomes are the crux of our nutrient delivery systems. Essentially, they are tiny spheres made with lipids, similar to the lipid membranes that make up the walls of your cells. When we say “Liposomal Vitamin C”, we’re referring to Vitamin C molecules sitting within protective lipid spheres: this is how we transport precious cargo at a tiny scale!
We utilise patented Nutrient Delivery Systems to create products that are clinically proven to perform 4x better than conventional supplements. This unique nutrient delivery system technology means we can wrap nutrients in lipids in both a liquid and a dry format - so whether you go for our great tasting sachets or the newly added capsules, the high bioavailability is still there.
To demonstrate the shielding ability of our liposomes, we commissioned a study which simulated the acidic conditions of both the stomach and the intestines, and measured how Zooki products held up in comparison to nutrients in their raw, unprotected form. Zooki's nutrients maintained quadruple the nutrient concentration in the stomach and intestines throughout digestion vs a standard supplement.
To demonstrate the increased bioavailability of Zooki Liposomal Delivery Technology, we commissioned an open label, randomised, single dose, two-treatment, two-way crossover, oral bioavailability study in healthy, adult, human participants under fasting conditions with a global top 500 university.
The study found over a 48 hour period, there was 3.91 x more Vitamin C in the bloodstream when using Zooki Liposomal Delivery Technology compared to non-encapsulated Vitamin C.
To demonstrate the improvements in cellular bioavailability, we commissioned independent in-vitro studies that examined how Zooki Vitamin C impacted cellular bioavailability and also efficacy with respect to combatting toxicity inside cells when compared to non-encapsulated Vitamin C.
The permeability assay values of both samples found Zooki liposomal vitamin C to have 3.2 x higher cellular uptake than conventional vitamin C.
Zeta potential tells us about the stability of liposomes, as it measures the difference in charge between the surface of the liposome and the solution itself. The higher the zeta potential, the more stable and less likely to aggregate are the liposomes. Zeta Potentials greater than 30 mV (either positive or negative) are considered to be stable. Both our dry and liquid delivery systems demonstrated a negative charge with a greater value than 30mV, indicating stability and integrity of our liposomal structures.
Dynamic light scattering (DLS) is a way to test how the intensity of light scattered by suspended particles changes over time. With liposomes, a narrow distribution indicates stability and a small particle will lend itself well to bioavailability. So, we’re looking for small liposomes that don’t vary too much in size. When tested, both our dry and liquid formats demonstrated a narrow distribution and small particle size, indicating high bioavailability and stability.
